Medicine

Accelerating ASO treatments coming from growth to implementation

.Contending rate of interests.R.S., M.S., H.G. as well as A.A.R. are coordinators of the 1M1M campaign. H.G. and A.A.R. are actually panel of supervisors members and also R.S., M.S. and also A.A.R. are actually participants of the scientific consultatory committee of N1C. A.A.R. reveals job through LUMC, which has licenses on exon-skipping technology, some of which has actually been actually licensed to BioMarin and also subsequently sublicensed to Sarepta. As co-inventor of some of these patents, A.A.R. was actually entitled to a reveal of nobilities. A.A.R. additionally divulges functioning as impromptu expert for PTC Rehabs, Sarepta Therapies, Regenxbio, Dyne Therapies, Lilly, BioMarin Pharmaceuticals Inc., Eisai, Entrada, Takeda, Splicesense, Galapagos, Sapreme, Italfarmaco and also Astra Zeneca. Over the last 5 years, A.A.R. also did ad hoc consulting for Alpha Anomeric. A.A.R. additionally reports membership of the clinical advisory boards of Eisai, Hybridize Therapies, Muteness Therapies, Sarepta Therapies, Sapreme and Mitorx. Over the last 5 years, A.A.R. was additionally a clinical advisory board member for ProQR. Wage for A.A.R. u00e2 s consulting and urging tasks is paid for to LUMC. Over the last 5 years, LUMC likewise received speaker honoraria from PTC Therapeutics, Alnylam Netherlands, Italfarmaco and Pfizer and cashing for deal study coming from Sapreme, Eisai, Galapagos, Synaffix and also Alpha Anomeric. Task funding is actually gotten coming from Sarepta Therapeutics as well as Entrada by means of unconstrained grants. H.G. has nothing to reveal in connection with the subjects dealt with within this document. Previously 5 years, he has actually also gotten consultancy gratuity from UCB. M.S. acquired consultancy gratuity coming from Ionis, UCB, Prevail, Orphazyme, Biogen, Servier, Reata, GenOrph, AviadoBio, Biohaven, Zevra, Lilly and also Solaxa in the past 5 years, all unrelated to today manuscript. R.S. has absolutely nothing to disclose in relation to the topics dealt with in this particular document. She has actually obtained audio speaker and/or working as a consultant gratuity or sponsoring contributions from Abbvie, Bial, STADA as well as Everpharma over the last 5 years.